Business & Technology
Oxford University linked UK de-aging firm in £2.7m collapse
Liquidators for OxStem Limited, which was based on Park End Street in Oxford, has asked for those who claim to be owed money by the firm to prove their debts by June 19.
In particular this call is aimed at ‘unsecured creditors’, meaning an individual or business which has loaned money without taking collateral to secure the debt.
READ MORE: Award-winning UK housebuilder collapses with £1.4m owed and jobs lost
In the latest document on Companies House (dated to May 2025) these are estimated at totalling £15,448, but a further claim worth over £3m from Oxford University is reportedly subject to arbitration proceedings.
This follows the collapse of the company which once raised £16.9m in order to fight age-related conditions such as cancer and neurodegenerative diseases including Alzheimer’s.
First founded in 2014, the biotech firm announced the almost £17m investment in 2016, with it representing a record amount for a UK academic spinout – a company designed to commercialise research – at the time.
OxStem was based at Park End Street (Image: Google Maps)
According to Fierce Biotech – which reported on the investment – this followed other firms which were looking to ‘cure old age’, with the money going towards developing small-molecule drugs that can activate repair mechanisms that already exist within the body.
Among those cited as founders of the firm were several Oxford University scientists including Professor Steve Davies and Professor Angela Russell.
Both individuals are associated with the Department of Chemistry.
Professor Davies said in 2016: “We are tackling many of the worst conditions associated with ageing: dementia, heart failure, cancer and macular degeneration, which is the leading cause of blindness in the developed world.”
Oxford University (Image: Other)
In addition a number of subsidiary companies were founded including OxStem Ocular and OxStem Neuro, which have since either been dissolved or are also in liquidation.
In 2019, things seemingly remained positive for the firm with reports indicating that they were looking for funding so their ‘regenerative medicine strategy’ could advance to clinical trials.
However, following that, financial difficulties appeared and in 2022 liquidators from Quantuma Advisory Limited were appointed.
In its financial accounts to June 2021, OxStem revealed creditors falling due within one year of £2.7 million, although it also reported cash at the bank and in hand of £2.4 million.
READ MORE: Leading UK charity collapses with £430K owed and jobs lost
At that time the average number of employees on the books was nine, with all staff having since been dismissed.
Though the company had already collapsed, the liquidation proved more complex in part because of the University of Oxford’s creditor claim and due to complexities around the selling of assets.
As such, the liquidation process is still ongoing.
Business & Technology
Over 100 MPs call for Thames Water to go into special administration
One hundred and 12 members of parliament have signed an open letter to the environment secretary and Ofwat, the water services regulation authority, calling for Thames Water to be placed into special administration without delay.
Since June 2025, Thames Water creditors, a group of US hedge funds, has been negotiating with Ofwat to formally take over the utility.
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Calum Miller MP (Image: Office of Calum Miller MP)
The proposed deal includes waiving fines for the water company, suspend pollution and performance targets, and raise bills for households beyond the level currently set by Ofwat.
Calum Miller, MP for Bicester and Woodstock, Olly Glover, MP for Didcot and Wantage, Freddie Van Mierlo, MP for Henley and Thame, Layla Moran, MP for Oxford West and Abingdon, and Charlie Maynard, MP for Witney all signed the list.
In total 53 Liberal Democrats signed the list, 46 Labour MPs, six independents, five Green party MPs, one from Plaid Cymru and one from the Conservative party.
Freddie Van Mierlo (Image: South Oxfordshire District Council.)
The letter highlights the dangerous possibilities of the company setting its own rules would create a dangerous precedent for all of England’s privatised water companies.
Thames Water was responsible for a third of the worst pollution incidents in 2025.
The CEO of the company, Chris Weston, recently drew controversy for saying that some of the firm’s targets were beyond what they could achieve.
The comments came after he gave himself a 14 per cent pay rise to £1.163 million in the year to March, while other directors received bonuses totalling £4.1 million
Business & Technology
Professor says tokenised deposits won’t transform banking
A Loughborough University study has challenged claims that tokenised bank deposits will transform banking, arguing that many of the supposed benefits can already be delivered through existing systems.
The paper examines tokenised deposits, which represent money held in a bank account as a digital token, and questions whether they amount to a significant innovation for mainstream banking. Supporters say the model could improve the speed and automation of payments. The study argues that these outcomes do not depend on tokenisation.
Professor Alistair Milne of Loughborough Business School wrote the policy note for SUERF, a group that brings together central bankers, regulators, academics and finance professionals. He argues that banks already use computer systems and databases that can be programmed to handle many of the same tasks now being presented as new.
Debate over digital money has gathered pace as banks, policymakers and financial technology groups explore alternatives to traditional account-based systems. Tokenised deposits have emerged as one of several concepts under discussion, alongside stablecoins and central bank digital currencies. Advocates say they could help create faster payments, available at all hours and easier to link to automated instructions.
Milne’s paper takes a narrower view of what is actually new. It argues that blockchain, the record-keeping technology often associated with cryptocurrencies such as Bitcoin, is not necessary for most of the practical gains linked to tokenised deposits. In his assessment, conventional bank infrastructure can already support much of the same functionality without converting deposits into tokens.
“Much of the current discussion suggests tokenised deposits will transform banking. My research indicates that the technology itself is not the key issue. Most of the promised advantages can already be achieved using conventional banking systems. In many cases, tokenised deposits are better understood as a new way of packaging existing capabilities rather than a fundamentally new form of money,” said Professor Alistair Milne, Loughborough Business School, Loughborough University.
The study does not dismiss tokenised deposits entirely. Instead, it identifies a limited set of circumstances in which they may offer a clearer advantage, particularly within the operations of large international banks serving corporate clients across several markets.
Cross-border use
One of the stronger use cases, the paper argues, arises when a global company moves money between countries and currencies within the same banking group. In that situation, payments can be automated more easily because the transfer remains within one bank’s internal systems rather than moving through several institutions.
That distinction matters because payments between different banks still require interbank settlement. This brings a series of established constraints, including regulation, security checks and the management of financial risk between institutions.
The paper argues that tokenising a deposit does not remove those underlying frictions. Even if the customer-facing representation of money changes, banks must still complete the same core settlement and compliance steps when funds move across institutional boundaries.
Wider debate
The findings add to a broader policy discussion over whether new forms of digital money represent genuine structural change or simply a redesign of existing financial processes. Banks and regulators have been assessing how far distributed ledger systems can improve payments, settlement and record-keeping, especially in wholesale and cross-border markets.
Milne’s intervention is likely to resonate with those who question whether the financial sector is overstating the novelty of token-based systems. The paper suggests the real barriers to better payments are not always technological, but often lie in the legal, regulatory and risk frameworks that govern transactions between separate institutions.
The paper also highlights a divide in the digital money debate. Some proposed systems promise gains by changing the form of money itself, while others seek improvements through better integration of existing infrastructure. Milne’s argument places tokenised deposits closer to the second category.
For banks, that could shape investment decisions. If the same results can be achieved through upgrades to current databases and payment systems, the commercial case for shifting to tokenised deposits may be weaker than some advocates suggest, especially in domestic banking where established systems are already deeply embedded.
At the same time, the paper leaves room for more targeted adoption where specific operational benefits can be shown. Large multinational banks handling internal cross-border flows may still find token-based structures useful in defined cases, even if the model falls short of a broader banking revolution.
The study’s central conclusion is that the hardest parts of modern payments do not disappear simply because deposits are represented differently in software. As Milne argues, the most important constraints often emerge when money must move between institutions rather than within them.
Those frictions remain central to banking, regardless of whether a deposit is recorded in a conventional account ledger or represented as a token. The paper argues that turning deposits into digital tokens does little to remove these underlying challenges.
Business & Technology
UK restaurant chain bids final farewell in emotional goodbye
The closures, including branches in Oxfordshire, are part of the parent company Whitbread’s major restructuring plan, and will see all 106 sites shut permanently.
It was announced in April that the company would shut its remaining Beefeater and Brewers Fayre sites as part of a strategy overhaul, placing around 3,800 jobs at risk.
READ MORE: More than 100 restaurants to shut across the UK
There are Beefeaters in Cowley and Kidlington.
Now the chain has reached out to its loyal customers.
Dishes are served at Beefeater (Image: Jamie Lau)
In an email being distributed to previous diners and members of its loyalty schemes, Beefeater shared a message of gratitude, with two prominent words: ‘thank you’.
It said: “A message from your local Beefeater: We want to say a huge thank you for your custom at our Beefeater restaurants.”
It added: “As you may have seen, we have recently announced changes to our business, which is resulting in the closure of our Branded Restaurants.
“This means that on Thursday, September 10, 2026, your local Beefeater and all other UK Beefeaters will close.”
Inside Beefeater (Image: Christie Owen & Davies)
In the letter, the company also said it would close the loyalty scheme on August 31.
The restructure is part of Whitbread’s new five-year strategy, which aims to reduce costs by £250m.
The chain first launched in 1974.
The former Ock Mill Beefeater restaurant in Abingdon (Image: Andy Ffrench)
Several customers said they were “sad” to see the chain shutting sites, although they also felt the brand had gone downhill in more recent years.
One person wrote: “Until I went to university the only restaurant I’d ever been to was a Beefeater. We’d go for various family birthdays. I absolutely loved it.
“A steak or a mixed grill, which I never got at home, followed by a Knickerbocker Glory. Fantastic times. I went back a couple of years ago.
“The place looked run down. I feel sad about this, but I guess the fact I hadn’t been to one for 30 years is part of the problem.”
The Ock Mill Beefeater restaurant, linked to the former Premier Inn in Marcham Road, Abingdon, closed in 2023, and the site was bought by the Unicorn School, which is currently renovating the building for classrooms.
Dominic Paul, Whitbread’s chief executive, said earlier: “We always challenge ourselves to improve and, in light of significant cost increases in the form of business rates and national insurance, as well as the implied market discount to our inherent value, we’ve looked hard at the options open to us to maximise value creation over the medium and long-term.
“This has been a rigorous process, and we’ve approached all options with an open mind.
“Our new five-year plan builds on our strengths and drives a significant acceleration of our strategy.”
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