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Oxford University linked UK de-aging firm in £2.7m collapse

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Liquidators for OxStem Limited, which was based on Park End Street in Oxford, has asked for those who claim to be owed money by the firm to prove their debts by June 19.

In particular this call is aimed at ‘unsecured creditors’, meaning an individual or business which has loaned money without taking collateral to secure the debt.

READ MORE: Award-winning UK housebuilder collapses with £1.4m owed and jobs lost

In the latest document on Companies House (dated to May 2025) these are estimated at totalling £15,448, but a further claim worth over £3m from Oxford University is reportedly subject to arbitration proceedings.

This follows the collapse of the company which once raised £16.9m in order to fight age-related conditions such as cancer and neurodegenerative diseases including Alzheimer’s.

First founded in 2014, the biotech firm announced the almost £17m investment in 2016, with it representing a record amount for a UK academic spinout – a company designed to commercialise research – at the time.

OxStem was based at Park End Street (Image: Google Maps)

According to Fierce Biotech – which reported on the investment – this followed other firms which were looking to ‘cure old age’, with the money going towards developing small-molecule drugs that can activate repair mechanisms that already exist within the body.

Among those cited as founders of the firm were several Oxford University scientists including Professor Steve Davies and Professor Angela Russell.

Both individuals are associated with the Department of Chemistry.

Professor Davies said in 2016: “We are tackling many of the worst conditions associated with ageing: dementia, heart failure, cancer and macular degeneration, which is the leading cause of blindness in the developed world.”

Oxford University (Image: Other)

In addition a number of subsidiary companies were founded including OxStem Ocular and OxStem Neuro, which have since either been dissolved or are also in liquidation.

In 2019, things seemingly remained positive for the firm with reports indicating that they were looking for funding so their ‘regenerative medicine strategy’ could advance to clinical trials.

However, following that, financial difficulties appeared and in 2022 liquidators from Quantuma Advisory Limited were appointed.

In its financial accounts to June 2021, OxStem revealed creditors falling due within one year of £2.7 million, although it also reported cash at the bank and in hand of £2.4 million.

READ MORE: Leading UK charity collapses with £430K owed and jobs lost

At that time the average number of employees on the books was nine, with all staff having since been dismissed.

Though the company had already collapsed, the liquidation proved more complex in part because of the University of Oxford’s creditor claim and due to complexities around the selling of assets.

As such, the liquidation process is still ongoing.





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Business leaders urge greener tech on World Environment Day

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SOFIAH NICHOLE SALIVIO

News Editor

Bentley Systems, Blue Cloud Softech Solutions and Trust International have urged governments and businesses to use World Environment Day as a catalyst for more rigorous environmental action. As pressure on digital systems and supply chains grows, the organisations pointed to infrastructure resilience, sustainable data centres and product lifecycle responsibility.

Executives from the three companies said climate change, resource use and e-waste are reshaping expectations across the technology and infrastructure sectors. Their comments reflect a shared view that environmental performance now sits alongside reliability and cost as a core measure of success.

Chris Bradshaw, Chief Sustainability & Education Officer at Bentley Systems, linked climate risk directly to the stability of basic services and economic activity.

“Continuity of operations has been a government and business imperative since the dawn of civilization. Today, resilient infrastructure is the absolute key to the continuity of society itself.”

He said the combination of climate change, ageing infrastructure and cyber risk is exposing weaknesses in existing systems.

“Yet, that continuity is under unprecedented threat. While accelerating climate change and extreme weather remain the ultimate stress tests for our built environment, they are now compounded by aging legacy systems and cyber vulnerabilities. This World Environment Day is a stark reminder that climate resilience is an infrastructure necessity, and a merely reactive approach is no longer an option,” Bradshaw said.

He argued that operators and public authorities need earlier insight into where disruption may occur, stressing the role of data and modelling in long-term resilience planning.

“We must anticipate climate and operational disruption before it strikes. By combining deep engineering expertise with digital intelligence, we can build and better manage physical infrastructure networks that actually endure. The leaders who embrace data-driven resilience today will be the ones safeguarding our environment and essential services tomorrow,” Bradshaw said.

Rising demand for artificial intelligence and cloud services is intensifying scrutiny of how data facilities use energy and water. Blue Cloud Softech Solutions is positioning sustainable design as a core requirement for its AI data centre projects.

“World Environment Day is a timely reminder to rethink how we build and operate digital infrastructure. As demand for AI and data processing continues to grow, sustainability must remain a priority. At BCSSL, we are focused on developing energy-efficient AI data centres that incorporate eco-friendly cooling technologies designed to reduce water consumption and improve operational efficiency. By adopting smarter, resource-conscious infrastructure and supporting renewable energy integration through initiatives such as Blue Energy, we aim to minimise environmental impact while building future-ready digital ecosystems that are powerful, resilient, and responsible by design,” said Mohan Krishna Pathalapati, Chief Operating Officer, Blue Cloud Softech Solutions.

The remarks reflect growing concern among policymakers and regulators about the environmental impact of large-scale computing. As digitalisation accelerates, operators face closer scrutiny of power sourcing, water use and equipment lifespans.

Product design and manufacturing practices are also under pressure. In the consumer electronics sector, Trust International is drawing attention to the climate footprint of devices long before they reach end of life.

“World Environment Day is a timely annual check-in reminding us that meaningful climate action is rarely driven by a single breakthrough. More often, it is the result of incremental improvements made consistently over time. The challenge facing the electronics industry highlights exactly why this approach matters. More than 80% of a headset’s climate footprint can be generated during manufacturing, while global e-waste is expected to surpass 80 million tonnes by 2030. These figures show that sustainability cannot be treated as an end-of-life issue but as a concern at every stage of a product’s lifecycle, from sourcing materials and manufacturing to packaging, use, and eventual disposal. At Trust, we have focused on every decision regarding the creation, sourcing and eventual clearance of our products. Over the past year, this has included increasing the use of recycled materials, reducing plastic and foam packaging by 25% and 32% respectively, and continuing to strengthen the standards and certifications that help validate our progress. Achievements such as maintaining EcoVadis Gold status for five consecutive years demonstrate the value of turning ambition into measurable action. As scrutiny around environmental performance continues to grow, businesses will increasingly be judged not by the sustainability targets they announce, but by the progress they can demonstrate. Independent certifications and transparent reporting play an important role in moving the needle for the industry to deliver meaningful results and, most importantly, for the betterment of the earth,” said Arjen Steenbergen, ESG Manager, Trust International.



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New five-storey labs could see 410 jobs relocated from 'ageing' buildings

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A new Oxfordshire five-storey lab facility at the Harwell Campus could see 410 jobs relocated if proposals are approved.



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CreatorOS launches Nutcake AI assistant for brands

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REGINE LAGUILLES

Continuous Improvement & Communications

CreatorOS has launched Nutcake, an artificial intelligence assistant for creator marketing, available free to brands and agencies.

The launch marks a shift for the London-based business beyond campaign management software into tools that automate more of the day-to-day work involved in influencer campaigns. Nutcake sits on top of CreatorOS’s existing platform, which has been used to run campaigns for brands including McDonald’s, Three, Crocs, Subway and Channel 4.

Nutcake is designed to handle tasks across strategy, creator discovery, brief writing, project management, contracting, payments and campaign delivery. Brands and agencies can enter campaign objectives, and the system will suggest creator styles and formats, produce a brief, and track workflow through to delivery and performance analysis.

Campaign automation

A central part of the launch is a competitive intelligence tool, available to brands and agencies free from the outset. It tracks creator collaborations in real time and is intended to help marketing teams monitor rival activity as sponsored posts go live.

According to CreatorOS, the data set behind the service already includes more than 500,000 sponsored #ad posts, with 50,000 more added each week, as well as a further 100,000 brand posts. The data is used to identify trends in content formats, hooks and messaging within specific categories.

Alongside the product launch, CreatorOS has made 15,000 vetted UK creator profiles publicly available on the platform. The database is aimed at brands and agencies looking for professional creators and includes direct agent contacts, rate card guidance and additional profile data.

The move reflects broader demand from marketers for tools that reduce manual work in creator campaigns, particularly as brands manage larger rosters of influencers across several platforms. It also places CreatorOS among a growing number of businesses applying artificial intelligence to advertising operations, research and workflow management.

Creator features

The platform also includes features aimed at creators. They can share audience data directly from Meta and TikTok APIs, communicate with brand partners through a WhatsApp integration and send pitches to brands through the platform.

CreatorOS has also added contract guidance tools intended to help creators understand agreement terms and negotiate fairer arrangements. These services are designed to improve the working relationship between brands commissioning campaigns and the people producing the content.

Agency growth

CreatorOS was founded in 2020 by Tim Mitchell and Will Cookson. Since then, it has worked with London agencies including Saatchi & Saatchi, Leo Burnett, Lucky Generals and BBH, according to the company.

Mitchell outlined the company’s position on the launch.

“The brands getting the most out of creator marketing are the ones who can move quickly, brief well and manage relationships at scale, and that’s exactly what Nutcake is built to deliver. What makes Nutcake powerful is what’s behind it: a connected ecosystem of brands and creators, years of proprietary data and a platform that has already delivered campaigns for some of the biggest brands in the market,” said Tim Mitchell, Chief Executive Officer, CreatorOS.

“Nutcake is the agentic layer that makes all of that work harder and faster for the people running campaigns day to day. When it writes a brief, identifies a creator or keeps a campaign on track, it’s drawing on something real. That’s what sets it apart,” added Mitchell.



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