Oxford University
Blood test may improve survival of childhood cancer in Africa
In a study published in Nature Medicine, researchers from the University of Oxford and the Muhimbili University of Health and Allied Sciences (MUHAS) in Dar es salaam, Tanzania, have shown that a minimally invasive “liquid biopsy” test can diagnose Burkitt lymphoma rapidly and accurately in sub-Saharan Africa, where delays in traditional testing often prove fatal.
Despite its aggressive nature, Burkitt lymphoma is often curable when treated quickly, with survival rates over 90%. Treatment is widely available and free-of-charge in most sub-Saharan countries, however current diagnostic tests demand specialist expertise and laboratory equipment that are often unavailable in resource-limited settings. Due to this, most children either remain undiagnosed or are diagnosed too late. In much of the region, survival rates can fall below 50%.
‘There is an urgent need for new diagnostic methods that are practical and effective in the under-resourced settings where Burkitt lymphoma is most common’, said Anna Schuh, Professor of Molecular Diagnostics at the University of Oxford and lead researcher on the study. ‘This is a highly treatable cancer, yet too many children and young adults are not diagnosed in time. As a minimally invasive and precise approach, liquid biopsy tests have enormous potential to transform diagnosis in sub-Saharan Africa and significantly improve outcomes.’
Liquid biopsies detect tiny amounts of DNA released by cancer cells into the blood. Using a simple blood sample, scientists can identify specific genetic changes that are characteristic of Burkitt lymphoma and distinguish them from DNA from healthy cells or other tumour types.
Professor Anna Schuh and her team in Oxford, working in collaboration with researchers at MUHAS in Tanzania, the Central Public Health Laboratory in Kampala, Uganda and four study sites in these countries have developed a minimally invasive liquid biopsy test for the rapid and precise detection of Burkitt lymphoma. This is the first indication that liquid biopsies might play a big role in diagnosing other cancers in sub-Saharan Africa.
The international research team evaluated the liquid biopsy test in a large group of children and young adults who presented with clinical signs of lymphoma across four hospitals in Uganda and Tanzania. Its performance was compared to a tissue biopsy-based approach that used diagnostic tests accessible in limited-resource settings.
High accuracy and faster results
The blood test demonstrated strong ability to distinguish Burkitt lymphoma from other conditions, achieving an overall accuracy of 98%. Among 81 patients with a confirmed tissue-based diagnosis of Burkitt lymphoma, 86.4% were correctly identified via liquid biopsy.
Importantly, the blood test dramatically reduced the time needed to reach a diagnosis. A liquid biopsy diagnosis was 40.3 days faster on average, compared to tissue biopsy diagnosis.
To understand how the test would perform in real-world clinical practice, the team held weekly multidisciplinary team (MDT) meetings to review cases in real time.
Clara Chamba, Head of Haematology at MUHAS and study author said: ‘Introducing liquid biopsy into our multidisciplinary meetings transformed how quickly we could start treating our patients. With liquid biopsy, 93% of cases were diagnosed within the first week of sample collection, compared to just 40% when we relied on tissue biopsy alone. For a cancer that progresses as quickly as Burkitt lymphoma, that time can be life-saving.’
While further work is needed to understand how to scale the test for clinical use, this study shows that liquid biopsy could serve as a complementary and timely diagnostic tool, especially where tissue biopsy access is limited or delayed. By increasing diagnostic yield and dramatically shortening time to diagnosis, this approach could help ensure that children with Burkitt lymphoma begin life-saving treatment sooner.
Professor Bruno Sunguya, Deputy Vice Chancellor, Research and Consultancy, MUHAS, Tanzania, said: ‘The successful implementation and analytical work conducted in Tanzania and Uganda demonstrates that precision medicine research can and should be led from within low- and middle-income countries. Beyond lymphoma, this work opens new opportunities to apply genomic and liquid biopsy technologies to strengthen cancer diagnosis and improve outcomes more broadly across the region. This collaboration reaffirms our commitment to advancing innovation, accelerating timely diagnosis, and improving survival for children and adults affected by cancer.’
‘Liquid biopsy for the diagnosis of EBV-positive Burkitt’s lymphoma in endemic areas‘ is published in Nature Medicine.
Oxford University
Celebrating highlights in literacy, digital learning and assessment, and research publishing
Our Annual Report for 2025/26 is now available
The report shares a number of publishing highlights in research and education, as well as our continued commitment to our global communities and to operating sustainably.

Professor Irene Tracey
“I am so incredibly proud of what OUP contributes to Oxford and the world. The dedication of the leadership and staff, board members, and academic delegates is evident in their service to the Press.
“As we collectively balance the human need to create, tell, and share stories as the world around us changes at pace, I am confident that my colleagues at OUP will continue to uphold our long-held traditions while shaping the new.”
Nigel Portwood
“This has been a year of investment, innovation, and growth for OUP. Against a changing backdrop in some of our markets, we remained focused on fulfilling our mission by expanding our publishing portfolio, embracing new technologies, and developing tools and services to support learning and research across the world.”

The post Celebrating highlights in literacy, digital learning and assessment, and research publishing appeared first on Oxford University Press.
Oxford University
Oxford University Press sheet music now available on Simply Piano
We’ve signed an agreement with Simply, the leading digital platform for creative hobbies, bringing select content from our acclaimed piano method to millions of Simply Piano learners worldwide.
What OUP content is available in Simply Piano?
Simply Piano users now have access to an expanded library of high-quality, curated sheet music spanning our works including Piano Time and Tunes for Ten Fingers, all within the app’s interactive learning environment.
Piano Time is one of our well-established beginner piano methods, widely appreciated for its natural progression and musical, engaging pieces. It helps students build reading, rhythm, coordination, and technique in a way that feels enjoyable rather than mechanical—which is why it has remained a trusted teaching resource for years.
Tunes for Ten Fingers is an introductory book for absolute beginners, encouraging security at every step and making learning fun.
These titles form part of our wider music publishing programme. We have long been a leader in classical music publishing, with a catalogue spanning centuries of repertoire and serving musicians from beginners to professionals. Through this collaboration, our music will now reach millions of Simply Piano hobbyists and lifelong learners worldwide.
OUP bringing sheet music content to Simply
Robin Barry, Director of Music at OUP, shared: “We are delighted to bring content from OUP’s piano method—trusted by teachers for generations—to the Simply Piano community, a platform that shares our commitment to quality and progression for aspiring musicians around the world.”
“Access to songs people love is one of the strongest drivers of learning,” said Yuval Kaminka, CEO and co-founder of Simply. “Working with OUP allows us to bring our learners and casual players sheet music of the highest editorial standard. It’s an important step in building a platform that supports learners at every stage and a proud moment for Simply.”
“What stands out in OUP’s early piano materials is the pedagogical clarity of the arrangements and pieces,” added Danny Fine, Simply Piano’s Music Pedagogy Lead. “They introduce new skills in a very structured and approachable way, which makes them especially effective for helping learners build confidence and gradually master core musical skills.”
As interest in creative hobbies grows globally, the addition of OUP’s portfolio strengthens Simply Piano’s library, giving users access to music they can both learn and enjoy.
Find out more about OUP’s sheet music here.
Oxford University
New research from Oxford University Press shows how children take life lessons from books
The findings of a new report from Oxford University Press, More than words: the real-life impact of reading, reveal how the majority of children believe that reading shapes how they treat others and helps them to navigate real-life situations.
The new research shows that three in five children (59%) believe what they have read in a book has helped them in a certain situation—such as being bullied, losing a family member, overcoming social anxiety, or starting a new school—highlighting that the benefits of reading go further than just understanding and comprehension. Other findings include:
- Seven in ten children (70%) said that reading helps them understand why people act the way they do
- More than two-thirds (68%) said it helps them think about how they treat other people
- While more than half (57%) of 12-14-year-olds continue to see the value of reading, both enjoyment and frequency of reading declines; 27% of 12-14-year-olds question its value in day-to-day life, with 17% undecided.
The report is based on a survey of 3,000 children aged 7-14 years old and 200 teachers across the UK, and with insights from the Oxford Children’s Corpus—the largest living database of children’s reading and writing in English in the world, containing over 500 million words.
Reading has an impact in real-life situations
82% of children agreed that stories remind them of things that happen in real life, showing the strong connection children make between what they read and their own experiences.
Our research also highlights the important role reading plays in helping children to understand and talk about their emotions. More than four in five children (84%) said reading helps them learn new words for feelings.
Teachers are seeing these benefits first-hand. Almost all teachers surveyed (95%) agreed that reading helps children develop their vocabulary, while three in five said they had witnessed a pupil gain a better understanding of an emotion through reading. More than nine in ten teachers (91%) identified empathy and perspective-taking as key benefits of reading.
Emotional themes are not confined to particular genres
Our research suggests that children do not necessarily seek out books about emotions directly but instead gravitate towards more entertaining books which can present real-life issues and emotions in accessible ways through humour or action.
When asked what genres they prefer to read, children said they were most drawn to funny stories (49%), adventure stories (40%), and fantasy stories (30%). However, many of the books cited alongside these genres—for example, Diary of a Wimpy Kid, Lottie Brooks, and Harry Potter—explored serious topics like conflict with friends, bullying, or bereavement.
A challenge with older readers
While children of all ages can gain emotional insights from a wide range of books and genres, the findings suggest that, as they get older, many need help maintaining their connection with reading.
Nearly three-quarters (72%) of children aged 7-10 said they liked reading, however, this fell to 59% among 11-14-year-olds. Reading frequency also dropped, with 79% of 7-10yr olds who said they read at least once a week, compared with just 61% of those aged 11-14.
One possible reason for this decline is that some older children do not see books as relevant to their daily lives. While 57% of 12-14-year-olds recognize the value of reading, one in four (27% of 12-year-olds; 25% of 13-year-olds; and 29% of 14-year-olds) disagreed that books had helped them navigate situations they have faced. A further 17% are neutral on the topic.
This presents an opportunity to provide more support to help older readers discover books that reflect their experiences and interests so that they feel reading is more meaningful and engaging.
Elizabeth Munn, Managing Director of OUP’s Education division, said: “This research shows how deeply children are engaging with the books they read and using them to make sense of the world around them. It’s incredible to see how children are actively applying what they read on a page to real life—whether that’s understanding the perspective of somebody else, navigating a situation in their own life, or reflecting on their own behaviour towards others.
“Children are growing up in an increasingly complex world. Our research reaffirms that reading remains one of the most powerful ways to help them develop empathy, confidence, and emotional understanding—skills that are just as important as academic success in equipping them for the future.”
The report also includes contributions from leading literacy and education organizations, including Book Aid International, EmpathyLab, and the National Literacy Trust.
Read the full report here.
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